‘After 2 weeks of CPAP withdrawal, OSA patients experienced considerable increases in heart rate and blood pressure as well as a deterioration in vascular function.’ The researchers recruited patients who was simply previously diagnosed with OSA and treated with CPAP and had been registered in a database of the SLEEP PROBLEMS Centre in Zurich. Individuals were randomized to either continue CPAP therapy or even to withdraw CPAP for 14 days. After baseline polysomnography, individuals underwent nightly at-home assessment of respiration and oxygen saturation every day of the study period. Patients had been assessed for subjective and objective sleepiness also, psychomotor performance, blood pressure and heart rate, endothelial function , systemic inflammation, insulin level of resistance and urinary catecholamines The polysomnography was repeated at the ultimate end of the two-week period.In patients with more severe lung infections, intravenous antibiotics might be required. Medications could also be used to loosen secretions, dilate bronchial tubes and decrease inflammation, decreasing the risk of infection hopefully. Routine utilized of inhaled steroids using a handheld puffer may decrease creation of secretions, allow dilation of bronchial tubes, and prevent progression of bronchiectasis. Inhaled steroids may not have enough anti-inflammatory activity, and in unusual instances, steroids taken orally may also be required. Bronchodilator and anticholinergic inhaled medications dilate bronchial tubes and increase ventilation into the lungs, rendering it easier for secretions to be cleared. The medication can be inhaled using a tactile hand held puffer or with a nebulizer machine.